SCHEMBL30189963

SCHEMBL30189963

COc1cnc2c(-c3nc4c(C)cc(OCCNS(=O)(=O)c5ccc(C)cc5)nc4s3)cc(C)cc2n1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 16/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783134 1.00 F2RL3 (0.69) F2RL3
SCHEMBL30187721 0.94 F2RL3 (0.66) F2RL3
SCHEMBL21395693 0.94 F2RL3 (0.66) F2RL3
SCHEMBL19782830 0.87 F2RL3 (0.89) F2RL3
SCHEMBL23463228 0.87 F2RL3 (0.54) F2RL3
SCHEMBL21379490 0.86 F2RL3 (0.64) F2RL3
SCHEMBL30187520 0.86 F2RL3 (0.64) F2RL3
SCHEMBL23405320 0.83 F2RL3 (0.54) F2RL3
SCHEMBL19783071 0.82 F2RL3 (0.85) F2RL3
SCHEMBL30187853 0.82 F2RL3 (0.85) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed