SCHEMBL30189969

SCHEMBL30189969

COc1cnc2c(-c3nc4cc(F)c(O[C@@H](C)[C@@H](C)O)cc4s3)cc(C)cc2n1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30187561 1.00 F2RL3 (0.67) F2RL3
SCHEMBL19783097 1.00 F2RL3 (0.67) F2RL3
SCHEMBL19783727 1.00 F2RL3 (0.67) F2RL3
SCHEMBL21379371 1.00 F2RL3 (0.67) F2RL3
SCHEMBL21395352 0.92 F2RL3 (0.63) F2RL3
SCHEMBL21395402 0.92 F2RL3 (0.68) F2RL3
SCHEMBL21379683 0.91 F2RL3 (0.56) F2RL3
SCHEMBL19782433 0.91 F2RL3 (0.56) F2RL3
SCHEMBL19783820 0.91 F2RL3 (0.56) F2RL3
SCHEMBL21379707 0.90 F2RL3 (0.67) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed