Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833250 | 1.00 | AAK1 (0.50) | AAK1PTGER1HDAC3HDAC4HDAC1 | |
| SCHEMBL23833248 | 1.00 | AAK1 (0.50) | AAK1PTGER1HDAC3HDAC4HDAC1 | |
| SCHEMBL30169241 | 0.89 | AAK1 (0.47) | AAK1PTGER1HDAC3HDAC4HDAC1 | |
| SCHEMBL22526458 | 0.89 | AAK1 (0.47) | AAK1PTGER1HDAC3HDAC4HDAC1 | |
| SCHEMBL23833065 | 0.89 | AAK1 (0.47) | AAK1PTGER1HDAC3HDAC4HDAC1 | |
| SCHEMBL30169243 | 0.88 | AAK1 (0.48) | AAK1PTGER1HDAC3HDAC4HDAC1 | |
| SCHEMBL22526454 | 0.88 | AAK1 (0.48) | AAK1PTGER1HDAC3HDAC4HDAC1 | |
| SCHEMBL28967220 | 0.88 | AAK1 (0.48) | AAK1PTGER1HDAC3HDAC4HDAC1 | |
| SCHEMBL27146597 | 0.87 | AAK1 (0.34) | AAK1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27008149 | 0.87 | AAK1 (0.34) | AAK1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121055-A1 | STAT DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |