SCHEMBL30196073

SCHEMBL30196073

CC(O)c1cccc(-c2ccc3[nH]cc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c3c2)c1

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 12/20 0.60
▸ MAPT P10636 2/20 0.46
▸ PTPN5 P54829 1/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ TRPV1 Q8NER1 1/20 0.43
▸ GOT1 P17174 1/20 0.43
▸ BAZ1A Q9NRL2 1/20 0.42
▸ MTOR P42345 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23207759 1.00 STING1 (0.60) STING1MAPTPTPN5MEN1KMT2A
SCHEMBL23207645 0.93 STING1 (0.61) STING1MAPTPTPN5MEN1KMT2A
SCHEMBL30196128 0.93 STING1 (0.61) STING1MAPTPTPN5MEN1KMT2A
SCHEMBL23166575 0.86 STING1 (0.61) STING1MAPTMEN1KMT2AHTT
SCHEMBL23167861 0.86 STING1 (0.73) STING1MAPTMEN1KMT2AHTT
SCHEMBL30196153 0.85 STING1 (0.63) STING1MAPTMEN1KMT2AHTT
SCHEMBL23207905 0.85 STING1 (0.63) STING1MAPTMEN1KMT2AHTT
SCHEMBL30195880 0.85 STING1 (0.65) STING1MAPTMEN1KMT2AHTT
SCHEMBL23208060 0.85 STING1 (0.65) STING1MAPTMEN1KMT2AHTT
SCHEMBL23207916 0.84 STING1 (0.64) STING1MAPTMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002320-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-01-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002320-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 STING1 1/4885MAPT 894/4885PTPN5 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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