Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 17/20 | 0.60 |
| ▸ | NPY1R | P25929 | 11/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.60 |
| ▸ | NPY2R | P49146 | 7/20 | 0.60 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31752209 | 0.98 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30661263 | 0.98 | NPY4R (0.57) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30531631 | 0.96 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31097734 | 0.96 | NPY4R (0.56) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31097710 | 0.96 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31097681 | 0.96 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31097683 | 0.96 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31097675 | 0.96 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31097729 | 0.96 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31097735 | 0.96 | NPY4R (0.55) | NPY4RNPY1RNPY5RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201257-A1 | DE-NOVO DESIGNED TRANSMEMBRANE POLYPEPTIDES AND THEIR USES IN CELLULAR IMMUNOTHERAPY | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-06-29 | — | — | US | disclosed |
| EP-4149494-A2 | DE-NOVO DESIGNED TRANSMEMBRANE POLYPEPTIDES AND THEIR USES IN CELLULAR IMMUNOTHERAPY | Yeda Research and Development Co. Ltd (IL) | 2023-03-22 | — | — | EP | disclosed |