SCHEMBL30197645

SCHEMBL30197645

Clc1cc(Cl)c(-c2nc(-c3cccc4ccccc34)co2)nc1-c1nc(-c2cccc3ccccc23)co1.[Co]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 2/20 0.44
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 4/20 0.42
HSD17B10 Q99714 4/20 0.42
CYP1A2 P05177 2/20 0.42
ATM Q13315 2/20 0.42
CYP2C19 P33261 1/20 0.42
RAB9A P51151 1/20 0.42
ENPP3 O14638 2/20 0.42
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP2A6 P11509 1/20 0.36
HPGD P15428 4/20 0.35
MAPT P10636 4/20 0.35
TP53 P04637 2/20 0.35
MAPK1 P28482 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30197720 0.83 ENPP1 (0.44) ENPP1ALDH1A1KDM4EHSD17B10CYP1A2
SCHEMBL30197782 0.83 ENPP1 (0.47) ENPP1ALDH1A1KDM4EHSD17B10CYP1A2
SCHEMBL30198017 0.83 ENPP1 (0.47) ENPP1ALDH1A1KDM4EHSD17B10CYP1A2
SCHEMBL30197628 0.78 SMO (0.47) ENPP1ALDH1A1KDM4EATMRAB9A
SCHEMBL30414742 0.77 ENPP1 (0.49) ENPP1ALDH1A1KDM4EHSD17B10ATM
SCHEMBL1199684 0.77 ENPP1 (0.49) ENPP1ALDH1A1KDM4EHSD17B10ATM
SCHEMBL30414741 0.77 ENPP1 (0.49) ENPP1ALDH1A1KDM4EHSD17B10ATM
SCHEMBL5610455 0.76 ENPP1 (0.55) ENPP1ALDH1A1KDM4EHSD17B10ATM
SCHEMBL4431583 0.73 ENPP1 (0.60) ENPP1ALDH1A1KDM4EHSD17B10CYP1A2
SCHEMBL23212810 0.72 MAPT (0.55) ENPP1ALDH1A1KDM4EHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115836041-B Process for producing optically active compound 住友化学株式会社 2024-09-17 CN disclosed
CN-115836041-A Process for producing optically active compound 住友化学株式会社 2023-03-21 CN disclosed