SCHEMBL30197820

SCHEMBL30197820

Cc1cc(NC(=O)c2ccccc2)ccc1Nc1nccc(-c2cccnc2)n1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRA P16234 15/20 0.85
ABL1 P00519 12/20 0.85
BCR P11274 10/20 0.85
PDGFRB P09619 9/20 0.85
PRKCA P17252 5/20 0.85
EGFR P00533 1/20 0.85
SRC P12931 3/20 0.74
PRKCD Q05655 3/20 0.74
PRKD3 O94806 1/20 0.74
PRKCG P05129 1/20 0.74
PRKCB P05771 1/20 0.74
PRKCH P24723 1/20 0.74
PRKCI P41743 1/20 0.74
PRKCE Q02156 1/20 0.74
PRKCQ Q04759 1/20 0.74
PRKCZ Q05513 1/20 0.74
PRKD1 Q15139 1/20 0.74
KIT P10721 4/20 0.69
MAPK8 P45983 1/20 0.69
MAPK9 P45984 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12034590 0.95 PDGFRA (0.77) PDGFRAABL1BCRPDGFRBPRKCA
SCHEMBL29498750 0.92 PDGFRA (1.00) PDGFRAABL1BCRPDGFRBPRKCA
SCHEMBL9782 0.92 PDGFRA (1.00) PDGFRAABL1BCRPDGFRBPRKCA
Methane SCHEMBL5972158 0.91 PDGFRA (0.98) PDGFRAABL1BCRPDGFRBPRKCA
SCHEMBL3860520 0.89 PDGFRA (0.87) PDGFRAABL1BCRPDGFRBPRKCA
SCHEMBL29249178 0.87 MAPK8 (0.79) PDGFRAABL1BCRPDGFRBPRKCA
SCHEMBL20652847 0.87 ABL1 (0.66) PDGFRAABL1BCRPDGFRBPRKCA
SCHEMBL2004455 0.87 PDGFRA (0.91) PDGFRAABL1BCRPDGFRBPRKCA
SCHEMBL3055349 0.87 PDGFRA (0.89) PDGFRAABL1BCRPDGFRBPRKCA
SCHEMBL4903275 0.86 ABL1 (0.81) PDGFRAABL1BCRPDGFRBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059926-A Heterocyclic degradation determinants for target protein degradation C4医药公司 2026-05-19 CN disclosed
CN-118318033-A Cell aggregate comprising pituitary hormone-producing cells and method for producing the same 住友制药株式会社 2024-07-09 CN disclosed
CN-118043447-A Method for preparing cell population containing pituitary tissue and cell population 住友化学株式会社 2024-05-14 CN disclosed
WO-2023054396-A1 METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS 住友化学株式会社 2023-04-06 WO disclosed
WO-2023277135-A1 METHOD FOR PRODUCING CELLS CONSTITUTING NASAL EPITHELIUM, AND CELL POPULATION INCLUDING CELLS CONSTITUTING NASAL EPITHELIUM OR PROGENITOR CELLS THEREOF 住友化学株式会社 2023-01-05 WO disclosed