Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 11/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.58 |
| ▸ | RPS6KA1 | Q15418 | 2/20 | 0.58 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | TEC | P42680 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934586 | 0.80 | ROCK1 (0.74) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL4932798 | 0.73 | ROCK1 (1.00) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL29620261 | 0.73 | ROCK1 (1.00) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL4935363 | 0.70 | ROCK1 (1.00) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL4936335 | 0.67 | ROCK1 (1.00) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL4935013 | 0.65 | ROCK1 (1.00) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL4935272 | 0.64 | ROCK1 (1.00) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL4937845 | 0.64 | ROCK1 (0.83) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL4934893 | 0.63 | ROCK1 (0.85) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 | |
| SCHEMBL4932740 | 0.62 | ROCK1 (0.84) | ROCK1CYP3A4CYP2D6CYP2C9RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118318033-A | Cell aggregate comprising pituitary hormone-producing cells and method for producing the same | 住友制药株式会社 | 2024-07-09 | — | — | CN | disclosed |
| CN-118043447-A | Method for preparing cell population containing pituitary tissue and cell population | 住友化学株式会社 | 2024-05-14 | — | — | CN | disclosed |
| WO-2023054396-A1 | METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS | 住友化学株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023277135-A1 | METHOD FOR PRODUCING CELLS CONSTITUTING NASAL EPITHELIUM, AND CELL POPULATION INCLUDING CELLS CONSTITUTING NASAL EPITHELIUM OR PROGENITOR CELLS THEREOF | 住友化学株式会社 | 2023-01-05 | — | — | WO | disclosed |