Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | HTT | P42858 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | USP2 | O75604 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054548 | 1.00 | MEN1 (0.71) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL30198371 | 0.86 | KDM4E (0.78) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24054514 | 0.86 | KDM4E (0.78) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24054850 | 0.86 | KDM4E (0.80) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24054922 | 0.85 | MEN1 (0.72) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24054913 | 0.85 | MEN1 (0.73) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24054523 | 0.84 | MEN1 (0.74) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24054515 | 0.83 | MEN1 (0.78) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL30198292 | 0.83 | MEN1 (0.78) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24054921 | 0.83 | HSP90AA1 (0.73) | MEN1KMT2AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153576-A1 | NOTCH INHIBITORS AND USES THEREOF | StemSynergy Therapeutics, Inc. (US) | 2023-03-29 | — | — | EP | disclosed |
| CN-115836056-A | NOTCH inhibitors and uses thereof | STEMSYNERGY疗法有限责任公司 | 2023-03-21 | — | — | CN | disclosed |