Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 15/20 | 0.75 |
| ▸ | CD99 | P14209 | 1/20 | 0.72 |
| ▸ | PDE2A | O00408 | 4/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21291969 | 1.00 | NT5E (0.75) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL21291962 | 0.91 | NT5E (0.68) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL21291982 | 0.91 | NT5E (0.67) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL21291981 | 0.90 | NT5E (0.71) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL21291989 | 0.90 | NT5E (0.66) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL21291978 | 0.90 | NT5E (0.66) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL19949155 | 0.90 | NT5E (0.81) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL21291965 | 0.88 | NT5E (0.73) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL21291964 | 0.88 | NT5E (0.73) | NT5ECD99PDE2AADORA3ADORA2A | |
| SCHEMBL30198879 | 0.88 | NT5E (0.73) | NT5ECD99PDE2AADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3529254-B1 | PRODRUGS OF CLOFARABINE | WU LAURENCE I (TW) | 2023-02-22 | — | — | EP | disclosed |