Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 5/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199330 | 1.00 | ESR2 (0.53) | ESR2NR1H2HDAC8SCN9AGHSR | |
| SCHEMBL29097900 | 1.00 | ESR2 (0.53) | ESR2NR1H2HDAC8SCN9AGHSR | |
| SCHEMBL17894538 | 0.91 | ESR2 (0.54) | ESR2NR1H2HDAC8GHSRACACB | |
| SCHEMBL30199503 | 0.91 | ESR2 (0.56) | ESR2NR1H2HDAC8GHSRHRH3 | |
| SCHEMBL29097854 | 0.91 | ESR2 (0.56) | ESR2NR1H2HDAC8GHSRHRH3 | |
| SCHEMBL30199064 | 0.87 | NR1H2 (0.55) | ESR2NR1H2GHSRHRH3MAPK1 | |
| SCHEMBL29098104 | 0.86 | CD274 (0.43) | ESR2SCN9AHRH3CD274 | |
| SCHEMBL29097944 | 0.84 | NR1H2 (0.56) | ESR2NR1H2GHSRHRH3MAPK1 | |
| SCHEMBL30199048 | 0.84 | NR1H2 (0.56) | ESR2NR1H2GHSRHRH3MAPK1 | |
| SCHEMBL14541717 | 0.84 | ESR2 (0.64) | ESR2NR1H2GHSRACACBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |