SCHEMBL30199907

SCHEMBL30199907

COc1ccc(Oc2cccc(C(=O)N3CCN(Cc4nc5ccc(C(=O)O)cc5n4C[C@@H]4CCO4)CC3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.54
▸ HTR1A P08908 1/20 0.51
▸ CYP2C8 P10632 1/20 0.51
▸ KCNH2 Q12809 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30200517 0.94 GLP1R (0.54) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL30199597 0.93 GLP1R (0.58) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL30199945 0.93 GLP1R (0.59) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL30199756 0.92 GLP1R (0.54) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL30199788 0.90 GLP1R (0.52) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL29103515 0.89 GLP1R (0.53) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL29826418 0.89 GLP1R (0.53) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL30200014 0.89 GLP1R (0.53) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL29103508 0.89 GLP1R (0.53) GLP1RHTR1ACYP2C8KCNH2
SCHEMBL30199549 0.88 GLP1R (0.51) GLP1RHTR1ACYP2C8KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459929-B2 GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use CARMOT THERAPEUTICS INC. (US) 2025-11-04 — — US disclosed
US-20250154137-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE CARMOT THERAPEUTICS, INC. 2025-05-15 — — US disclosed
US-20240252492-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE CARMOT THERAPEUTICS, INC. 2024-08-01 — — US disclosed
US-20230089073-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE CARMOT THERAPEUTICS, INC. 2023-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154137-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE GLP1R, GCGR, GIPR GLP1R 1/4885HTR1A 65/4885CYP2C8 1543/4885
US-20230089073-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE GLP1R, GCGR, GIPR GLP1R 1/4885HTR1A 65/4885CYP2C8 1543/4885
US-20240252492-A1 GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE GLP1R, GCGR, GIPR GLP1R 1/4885HTR1A 65/4885CYP2C8 1543/4885
US-12459929-B2 GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods for their use GLP1R, GCGR, GIPR GLP1R 1/4885HTR1A 65/4885CYP2C8 1543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback