SCHEMBL30200550

SCHEMBL30200550

CN(C)c1ccc(C(c2ccccc2)c2ccccc2)c(N(C)C)c1N(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.35
HRH1 P35367 3/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CHEK1 O14757 1/20 0.32
NEK2 P51955 1/20 0.32
LIMK1 P53667 1/20 0.32
DYRK1A Q13627 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
AOC3 Q16853 6/20 0.32
EP300 Q09472 1/20 0.32
KAT2B Q92831 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29687122 0.85 MAPT (0.39) HTR2AHRH1MEN1MAPTCYP2C9
SCHEMBL6247039 0.72 HTR2A (0.40) HTR2AHRH1MEN1MAPTCYP2C9
SCHEMBL9757011 0.72 GAA (0.39) MAPTKMT2ATDP1KDM4EALDH1A1
SCHEMBL8813995 0.71 KCNB1 (0.40) HTR2AHRH1MEN1MAPTCYP2C9
SCHEMBL6556912 0.70 AOC3 (0.36) HTR2AHRH1MEN1MAPTCYP2C9
SCHEMBL6854837 0.69 MAPT (0.41) HTR2AHRH1MEN1MAPTCYP2C9
SCHEMBL10368854 0.68 HTR2A (0.34) HTR2AHRH1MEN1MAPTCYP2C9
SCHEMBL5009573 0.67 MAPT (0.48) MEN1MAPTCYP2C9KMT2ATDP1
SCHEMBL10753818 0.67 MAPT (0.37) HTR2AHRH1MEN1MAPTCYP2C9
SCHEMBL5550942 0.66 HTR2A (0.34) HTR2AHRH1MEN1MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4373898-A1 ACRYLATE ADHESIVE FOR CONTACT WITH LIQUID COOLANT Zephyros Inc. (US) 2024-05-29 EP disclosed
WO-2023001806-A1 ACRYLATE ADHESIVE FOR CONTACT WITH LIQUID COOLANT ZEPHYROS, INC. (US) 2023-01-26 WO disclosed