Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15465002 | 1.00 | POLB (0.39) | POLBPIK3CAPIK3CDPIK3CBPIK3CG | |
| Formic Acid SCHEMBL28851354 | 0.96 | POLB (0.40) | POLBPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL25090413 | 0.92 | GAA (0.39) | POLBGAAOXTRKDM4EALDH1A1 | |
| SCHEMBL14934588 | 0.91 | POLB (0.41) | POLBGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29481979 | 0.91 | POLB (0.41) | POLBGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL20073167 | 0.91 | POLB (0.38) | POLBGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL25090187 | 0.91 | POLB (0.38) | POLBGAAOXTRKDM4EALDH1A1 | |
| SCHEMBL29481973 | 0.90 | POLB (0.40) | POLBKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15463758 | 0.90 | POLB (0.39) | POLBGAAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL15464546 | 0.89 | HDAC8 (0.39) | POLBGAAKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028056-A1 | 3-AMINO PIPERIDYL SODIUM CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |