Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 17/20 | 1.00 |
| ▸ | CD274 | Q9NZQ7 | 17/20 | 1.00 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897446 | 1.00 | PDCD1 (1.00) | PDCD1CD274KDRTRPV1ABL1 | |
| SCHEMBL19897441 | 0.85 | PDCD1 (0.74) | PDCD1CD274KDRTRPV1 | |
| SCHEMBL30201399 | 0.85 | PDCD1 (0.74) | PDCD1CD274KDRTRPV1 | |
| SCHEMBL18979729 | 0.84 | PDCD1 (0.73) | PDCD1CD274 | |
| SCHEMBL19897432 | 0.82 | PDCD1 (0.69) | PDCD1CD274 | |
| SCHEMBL19897408 | 0.81 | CD274 (0.69) | PDCD1CD274 | |
| SCHEMBL19785839 | 0.79 | PDCD1 (0.66) | PDCD1CD274KDRTRPV1 | |
| SCHEMBL19779678 | 0.79 | PDCD1 (0.66) | PDCD1CD274KDRTRPV1 | |
| SCHEMBL29893697 | 0.79 | PDCD1 (0.66) | PDCD1CD274KDRTRPV1 | |
| SCHEMBL19897456 | 0.78 | PDCD1 (0.64) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504198-B1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORP (US) | 2023-01-25 | — | — | EP | claimed |