Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 15/20 | 0.51 |
| ▸ | CCNK | O75909 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.48 |
| ▸ | CCR7 | P32248 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25082915 | 1.00 | CCR6 (0.51) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25082643 | 0.89 | CCR6 (0.53) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL30201794 | 0.89 | CCR6 (0.53) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL30202163 | 0.89 | CCR6 (0.52) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25082716 | 0.89 | CCR6 (0.52) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25082729 | 0.89 | CCR6 (0.52) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL30201842 | 0.88 | CCR6 (0.56) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL26094659 | 0.88 | CCR6 (0.56) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL25079858 | 0.88 | CCR6 (0.68) | CCR6CCNKCCNA2CDK2CDK12 | |
| SCHEMBL30284766 | 0.88 | CCR6 (0.68) | CCR6CCNKCCNA2CDK2CDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387609-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023532-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |