SCHEMBL30203995

SCHEMBL30203995

CN(C)c1cccc2c(S(=O)(=O)N3CCCC[C@H]3C(=O)O)cccc12

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.62
ATM Q13315 1/20 0.62
HTT P42858 2/20 0.54
KDM4E B2RXH2 1/20 0.50
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
BRD4 O60885 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CCR4 P51679 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26204985 1.00 KMT2A (0.62) KMT2AATMHTTKDM4ETSHR
SCHEMBL16675421 1.00 KMT2A (0.62) KMT2AATMHTTKDM4ETSHR
SCHEMBL31363195 0.96 KMT2A (0.60) KMT2AATMHTTKDM4ETSHR
SCHEMBL5743956 0.96 KMT2A (0.60) KMT2AATMHTTKDM4ETSHR
SCHEMBL5743967 0.96 KMT2A (0.60) KMT2AATMHTTKDM4ETSHR
SCHEMBL19697944 0.85 KMT2A (0.52) KMT2AATMKDM4ETSHRCASP1
SCHEMBL30338518 0.84 KMT2A (0.56) KMT2AATMKDM4ETSHRCASP1
SCHEMBL19689618 0.84 KMT2A (0.56) KMT2AATMKDM4ETSHRCASP1
SCHEMBL30338808 0.84 KMT2A (0.56) KMT2AATMKDM4ETSHRCASP1
SCHEMBL30204279 0.84 KMT2A (0.56) KMT2AATMKDM4ETSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179542-A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS CODEXIS INC (US) 2025-06-05 US disclosed
US-12286648-B2 Engineered proline hydroxylase biocatalysts for hydroxylation of chemical compounds CODEXIS, INC. (US) 2025-04-29 US disclosed
US-12247234-B2 Biocatalysts and methods for hydroxylation of chemical compounds CODEXIS, INC. (US) 2025-03-11 US disclosed
US-20230272354-A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2023-08-31 US disclosed
US-11634695-B2 Vectors for expression of biocatalysts CODEXIS, INC. (US) 2023-04-25 US disclosed
US-11549132-B2 Biocatalysts and methods for hydroxylation of chemical compounds CODEXIS, INC. (US) 2023-01-10 US disclosed