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SCHEMBL30205272

SCHEMBL30205272

CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 7/20 0.63
▸ NPY1R P25929 5/20 0.63
▸ NPY2R P49146 3/20 0.63
▸ FOLH1 Q04609 1/20 0.60
▸ BACE1 P56817 3/20 0.53
▸ ACE P12821 1/20 0.53
▸ IL1RN P18510 1/20 0.53
▸ ERAP2 Q6P179 1/20 0.53
▸ NPY5R Q15761 2/20 0.53
▸ KISS1R Q969F8 4/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30516166 0.93 NPY4R (0.60) NPY4RNPY1RNPY2RFOLH1ACE
SCHEMBL30516164 0.93 NPY4R (0.60) NPY4RNPY1RNPY2RFOLH1ACE
SCHEMBL29350874 0.93 FOLH1 (0.68) NPY4RNPY1RNPY2RFOLH1ACE
SCHEMBL29625332 0.93 NPY4R (0.60) NPY4RNPY1RNPY2RFOLH1BACE1
SCHEMBL30292649 0.93 NPY4R (0.60) NPY4RNPY1RNPY2RFOLH1BACE1
SCHEMBL30065621 0.92 NPY4R (0.64) NPY4RNPY1RNPY2RFOLH1BACE1
SCHEMBL29385598 0.91 FOLH1 (0.59) NPY4RNPY1RNPY2RFOLH1KISS1R
SCHEMBL29395643 0.90 FOLH1 (0.60) NPY4RNPY1RNPY2RFOLH1BACE1
SCHEMBL29822758 0.90 FOLH1 (0.66) NPY4RNPY1RNPY2RFOLH1ACE
SCHEMBL2474675 0.90 FOLH1 (0.69) NPY4RNPY1RNPY2RFOLH1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110507810-B Application of oligopeptide in preparation of medicine for treating or preventing renal ischemia-reperfusion injury 中国药科大学 2023-01-31 — — CN disclosed