Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034611 | 0.95 | MAPK14 (0.44) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL4034702 | 0.93 | MAPK14 (0.46) | BRAFMAPK14LYNMAPK9GPR142 | |
| SCHEMBL302540 | 0.88 | BRAF (0.48) | BRAF | |
| SCHEMBL4033283 | 0.88 | MAPK14 (0.45) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL4031903 | 0.85 | MAPK14 (0.45) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL302124 | 0.85 | MAPK14 (0.44) | BRAFMAPK14LYNMAPK9 | |
| SCHEMBL301937 | 0.82 | BRAF (0.51) | BRAF | |
| SCHEMBL4033518 | 0.81 | BRAF (0.49) | BRAF | |
| SCHEMBL4031661 | 0.80 | BRAF (0.51) | BRAF | |
| SCHEMBL4034395 | 0.80 | BRAF (0.54) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4850824-B2 | — | — | 2012-01-11 | — | — | JP | claimed |