SCHEMBL30207443

SCHEMBL30207443

CC(C)(C)OC(=O)N1CCC(CCC2CCN(c3ccc(NC4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 9/20 0.60
CRBN Q96SW2 9/20 0.60
GPR119 Q8TDV5 11/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333565 0.96 DDB1 (0.59) DDB1CRBNGPR119
SCHEMBL23783207 0.94 DDB1 (0.63) DDB1CRBNGPR119
SCHEMBL29535454 0.93 DDB1 (0.68) DDB1CRBN
SCHEMBL25027239 0.93 DDB1 (0.68) DDB1CRBN
SCHEMBL26329799 0.93 DDB1 (0.68) DDB1CRBN
SCHEMBL26329796 0.93 DDB1 (0.68) DDB1CRBN
SCHEMBL31334160 0.93 DDB1 (0.57) DDB1CRBNGPR119
SCHEMBL31701449 0.92 DDB1 (0.59) DDB1CRBNGPR119
SCHEMBL27162923 0.92 DDB1 (0.59) DDB1CRBNGPR119
SCHEMBL31334450 0.92 DDB1 (0.60) DDB1CRBNGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823124-A Compounds for targeted degradation of BRD9 C4医药公司 2025-04-15 CN disclosed
CN-115279370-B Compounds for targeted degradation of BRD9 C4医药公司 2025-01-10 CN disclosed
EP-4114392-A1 COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 C4 Therapeutics, Inc. (US) 2023-01-11 EP disclosed