Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484084 | 1.00 | MAPT (0.34) | MAPTCDK2CDK4CDK6MKNK1 | |
| SCHEMBL28935744 | 1.00 | MAPT (0.34) | MAPTCDK2CDK4CDK6MKNK1 | |
| SCHEMBL28935785 | 0.92 | MAPT (0.35) | MAPTMKNK1RETESR2NR1H2 | |
| SCHEMBL31484164 | 0.92 | MAPT (0.35) | MAPTMKNK1RETESR2NR1H2 | |
| SCHEMBL30207696 | 0.92 | MAPT (0.35) | MAPTMKNK1RETESR2NR1H2 | |
| SCHEMBL31484135 | 0.88 | — | — | |
| SCHEMBL28935770 | 0.87 | — | — | |
| SCHEMBL30207745 | 0.87 | — | — | |
| SCHEMBL31484108 | 0.87 | — | — | |
| SCHEMBL28848960 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611925-B | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-115611925-A | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-01-17 | — | — | CN | disclosed |