Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | GCK | P35557 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15879718 | 0.90 | CNR2 (0.45) | CNR2CNR1GCKABL1NPC1 | |
| SCHEMBL2730896 | 0.87 | CNR2 (0.49) | CNR2CNR1GCKABL1NPC1 | |
| SCHEMBL2733632 | 0.82 | CNR2 (0.42) | CNR2CNR1GCKABL1NPC1 | |
| SCHEMBL16862385 | 0.80 | CNR2 (0.41) | CNR2CNR1GCKABL1NPC1 | |
| SCHEMBL15879367 | 0.78 | CNR2 (0.44) | CNR2CNR1ABL1NPC1RAB9A | |
| SCHEMBL16862693 | 0.77 | CNR2 (0.39) | CNR2CNR1GCKABL1NPC1 | |
| SCHEMBL8329180 | 0.77 | CNR2 (0.53) | CNR2CNR1ABL1NPC1RAB9A | |
| SCHEMBL16862259 | 0.74 | CNR2 (0.37) | CNR2ABL1NPC1RAB9AKDR | |
| SCHEMBL8325829 | 0.73 | CNR2 (0.47) | CNR2CNR1GCKABL1NPC1 | |
| SCHEMBL29840601 | 0.71 | KDR (0.53) | CNR2ABL1NPC1RAB9AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611925-B | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-115611925-A | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-01-17 | — | — | CN | disclosed |