Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667368 | 1.00 | PRMT5 (0.39) | PRMT5WDR77ALDH1A1 | |
| SCHEMBL19684699 | 0.84 | PRMT5 (0.39) | PRMT5WDR77 | |
| SCHEMBL19667418 | 0.79 | ADCY5 (0.39) | PRMT5WDR77 | |
| SCHEMBL19667419 | 0.78 | ADCY5 (0.40) | PRMT5WDR77 | |
| SCHEMBL30207841 | 0.77 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL19679060 | 0.77 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL19667683 | 0.77 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL19679203 | 0.76 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL19667639 | 0.76 | PRMT5 (0.41) | PRMT5WDR77 | |
| SCHEMBL30207833 | 0.76 | PRMT5 (0.41) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890797-B | Substituted carbon nucleoside derivatives useful as anticancer agents | 辉瑞公司 | 2023-02-28 | — | — | CN | disclosed |