Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.61 |
| ▸ | CDK7 | P50613 | 5/20 | 0.54 |
| ▸ | CDK2 | P24941 | 6/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | CDK4 | P11802 | 2/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.52 |
| ▸ | CCND1 | P24385 | 2/20 | 0.52 |
| ▸ | CDK8 | P49336 | 2/20 | 0.52 |
| ▸ | CDK9 | P50750 | 2/20 | 0.52 |
| ▸ | CCNH | P51946 | 2/20 | 0.52 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.52 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | INSRR | P14616 | 1/20 | 0.51 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24962513 | 1.00 | GSK3B (0.61) | GSK3BCDK7CDK2CCNE1CCNT1 | |
| SCHEMBL33378024 | 0.89 | GSK3B (0.49) | GSK3BCDK7CDK2CCNE1CCNT1 | |
| SCHEMBL30083532 | 0.89 | CDK7 (0.50) | GSK3BCDK7CDK2CCNE1CCNT1 | |
| SCHEMBL17032296 | 0.89 | CDK2 (0.58) | GSK3BCDK7CDK2CCNE1CCNT1 | |
| SCHEMBL1370667 | 0.89 | CDK7 (0.66) | CDK7CDK2CCNE1CCNT1CDK1 | |
| SCHEMBL33377874 | 0.86 | CDK7 (0.50) | GSK3BCDK7CDK2CCNE1CCNT1 | |
| SCHEMBL30083581 | 0.85 | CDK2 (0.52) | GSK3BCDK7CDK2CCNE1CCNT1 | |
| SCHEMBL33378026 | 0.85 | CDK7 (0.73) | GSK3BCDK7CDK2CCNE1CCNT1 | |
| SCHEMBL12952862 | 0.84 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL12143382 | 0.84 | CDK7 (0.55) | CDK7CDK2CCNE1CCNT1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4717312-A1 | PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-01 | — | — | EP | disclosed |
| WO-2023001061-A1 | CDK7 SELECTIVE INHIBITORS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |