Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 7/20 | 0.55 |
| ▸ | DNMT3A | Q9Y6K1 | 5/20 | 0.55 |
| ▸ | DNMT3L | Q9UJW3 | 3/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.45 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999564 | 1.00 | USP2 (0.55) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL23999385 | 0.94 | USP2 (0.56) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL30210277 | 0.94 | USP2 (0.56) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL24006012 | 0.93 | DNMT1 (0.54) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL24003804 | 0.93 | USP2 (0.55) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL30180638 | 0.90 | DNMT1 (0.68) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL19151468 | 0.90 | DNMT1 (0.68) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL23999615 | 0.90 | DNMT1 (0.68) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL30180283 | 0.90 | DNMT1 (0.68) | USP2MAPTKMT2ADNMT1DNMT3A | |
| SCHEMBL23999729 | 0.89 | USP2 (0.55) | USP2MAPTKMT2ADNMT1DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118524833-A | AKT3 modulators | 乔治穆内公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |