Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 6/20 | 0.57 |
| ▸ | DNMT3A | Q9Y6K1 | 5/20 | 0.57 |
| ▸ | DNMT3L | Q9UJW3 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180389 | 1.00 | KMT2A (0.57) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL19151435 | 1.00 | KMT2A (0.57) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL25826601 | 0.93 | DNMT1 (0.53) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL22793632 | 0.90 | MAPT (0.59) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL30180758 | 0.90 | DNMT1 (0.69) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL19151433 | 0.90 | DNMT1 (0.69) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL31125056 | 0.90 | DNMT1 (0.69) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL19151333 | 0.89 | MAPT (0.60) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL30180798 | 0.87 | KMT2A (0.59) | KMT2AMAPTUSP2DNMT1DNMT3A | |
| SCHEMBL19151411 | 0.87 | KMT2A (0.59) | KMT2AMAPTUSP2DNMT1DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867562-A | AKT3 modulators | 乔治穆内有限责任公司 | 2023-03-28 | — | — | CN | disclosed |