Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099633 | 1.00 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL20516766 | 1.00 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL23429572 | 1.00 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL23429444 | 0.91 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL23429447 | 0.91 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL20517161 | 0.91 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL23429609 | 0.91 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL30210803 | 0.91 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL20516629 | 0.91 | MAP4K1 (0.80) | MAP4K1 | |
| SCHEMBL23429606 | 0.91 | MAP4K1 (0.80) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024411-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-110709392-B | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |