Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930563 | 1.00 | MEN1 (0.31) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL30210861 | 0.93 | MAPT (0.33) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL23930638 | 0.93 | MAPT (0.33) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL25197518 | 0.85 | — | — | |
| SCHEMBL23930554 | 0.85 | MEN1 (0.37) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL30210944 | 0.85 | MEN1 (0.37) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL30210917 | 0.84 | MEN1 (0.36) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL23930519 | 0.84 | MEN1 (0.36) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL23930600 | 0.83 | CNR2 (0.33) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL30210956 | 0.83 | CNR2 (0.33) | MEN1KMT2AMAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697979-B | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2025-06-24 | — | — | CN | claimed |
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | claimed |
| CN-115697979-B | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2025-06-24 | — | — | CN | disclosed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | disclosed |