Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | CSGALNACT1 | Q8TDX6 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930475 | 1.00 | NPC1 (0.38) | NPC1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL23930490 | 0.92 | MEN1 (0.44) | RAB9AKMT2ASMN1; SMN2POLBPTPN1 | |
| SCHEMBL23930626 | 0.92 | MEN1 (0.44) | RAB9AKMT2ASMN1; SMN2POLBPTPN1 | |
| SCHEMBL23930461 | 0.92 | MEN1 (0.44) | RAB9AKMT2ASMN1; SMN2POLBPTPN1 | |
| SCHEMBL30210845 | 0.91 | CDK5 (0.39) | NPC1RAB9AKMT2ALMNAPOLB | |
| SCHEMBL23930581 | 0.91 | CDK5 (0.39) | NPC1RAB9AKMT2ALMNAPOLB | |
| SCHEMBL30210947 | 0.90 | MAPT (0.39) | NPC1RAB9AKMT2ALMNAPOLB | |
| SCHEMBL23930507 | 0.90 | MAPT (0.39) | NPC1RAB9AKMT2ALMNAPOLB | |
| SCHEMBL23930564 | 0.88 | PTPN1 (0.38) | NPC1KMT2APTPN1MAPTCSGALNACT1 | |
| SCHEMBL30210974 | 0.88 | PTPN1 (0.38) | NPC1KMT2APTPN1MAPTCSGALNACT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697979-B | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2025-06-24 | — | — | CN | claimed |
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | claimed |