Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930575 | 1.00 | HIF1A (0.38) | HIF1APOLBSMN1; SMN2MLLT1MAPT | |
| SCHEMBL30210868 | 0.89 | NPC1 (0.41) | POLBSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL23930487 | 0.89 | NPC1 (0.41) | POLBSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL31411943 | 0.88 | SMN1; SMN2 (0.38) | HIF1APOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL25199172 | 0.88 | SMN1; SMN2 (0.38) | HIF1APOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL23930566 | 0.88 | SMN1; SMN2 (0.37) | HIF1APOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30210930 | 0.88 | SMN1; SMN2 (0.37) | HIF1APOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL23930596 | 0.88 | POLB (0.37) | HIF1APOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL30210895 | 0.88 | POLB (0.37) | HIF1APOLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL25547090 | 0.87 | SMN1; SMN2 (0.35) | HIF1APOLBSMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | claimed |
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | disclosed |