Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30210875 | 1.00 | KDM1A (0.32) | KDM1ASCN9ASCN10ASMYD3MEN1 | |
| SCHEMBL23930474 | 1.00 | KDM1A (0.32) | KDM1ASCN9ASCN10ASMYD3MEN1 | |
| SCHEMBL23930476 | 1.00 | KDM1A (0.32) | KDM1ASCN9ASCN10ASMYD3MEN1 | |
| SCHEMBL23930539 | 1.00 | KDM1A (0.32) | KDM1ASCN9ASCN10ASMYD3MEN1 | |
| SCHEMBL23930503 | 0.92 | NPC1 (0.35) | SCN9ASCN10ASMYD3MEN1MAPT | |
| SCHEMBL23930607 | 0.92 | NPC1 (0.35) | SCN9ASCN10ASMYD3MEN1MAPT | |
| SCHEMBL23930505 | 0.92 | NPC1 (0.35) | SCN9ASCN10ASMYD3MEN1MAPT | |
| SCHEMBL23930515 | 0.92 | NPC1 (0.39) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23930470 | 0.92 | NPC1 (0.39) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25209869 | 0.92 | NPC1 (0.39) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | claimed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | claimed |
| EP-4139287-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | disclosed |