Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930533 | 1.00 | CHRNA7 (0.46) | CHRNA7MAPTMEN1KMT2APOLB | |
| SCHEMBL23930549 | 0.90 | MAPT (0.53) | CHRNA7MAPTMEN1KMT2APOLB | |
| SCHEMBL30210963 | 0.83 | MAPT (0.45) | CHRNA7MAPTMEN1KMT2APOLB | |
| SCHEMBL23930591 | 0.83 | MAPT (0.45) | CHRNA7MAPTMEN1KMT2APOLB | |
| SCHEMBL23930611 | 0.83 | CCNA2 (0.50) | CHRNA7MAPTMEN1KMT2APOLB | |
| SCHEMBL31633457 | 0.83 | CCNA2 (0.50) | CHRNA7MAPTMEN1KMT2APOLB | |
| SCHEMBL30210806 | 0.81 | CHRNA7 (0.44) | CHRNA7MAPTMEN1KMT2APOLB | |
| SCHEMBL23930636 | 0.81 | CHRNA7 (0.44) | CHRNA7MAPTMEN1KMT2APOLB | |
| SCHEMBL23930497 | 0.81 | MEN1 (0.31) | MAPTMEN1KMT2ACDK5CDK5R1 | |
| SCHEMBL25207573 | 0.81 | MEN1 (0.31) | MAPTMEN1KMT2ACDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697979-B | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2025-06-24 | — | — | CN | disclosed |
| EP-4139287-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | disclosed |