SCHEMBL30211340

SCHEMBL30211340

O=C(Nc1ccccc1)c1ccccc1OC(F)(F)F

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 5/20 0.72
KCNK9 Q9NPC2 5/20 0.72
RXFP1 Q9HBX9 1/20 0.64
F2R P25116 1/20 0.64
SGMS2 Q8NHU3 1/20 0.57
PNLIP P16233 1/20 0.57
BRAF P15056 1/20 0.56
AVPR2 P30518 1/20 0.55
GPR27 Q9NS67 1/20 0.55
KMT2A Q03164 4/20 0.55
USP2 O75604 1/20 0.55
MAPT P10636 1/20 0.55
ALDH1A1 P00352 1/20 0.54
PKM P14618 1/20 0.53
MEN1 O00255 2/20 0.53
HPGD P15428 2/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
HTT P42858 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4753755 1.00 KCNK3 (0.72) KCNK3KCNK9RXFP1F2RSGMS2
Hydrochloric Acid SCHEMBL2105897 0.85 KCNK3 (0.70) KCNK3KCNK9RXFP1F2RPNLIP
SCHEMBL1197921 0.84 KCNK3 (0.73) KCNK3KCNK9RXFP1F2RPNLIP
SCHEMBL22819921 0.83 RXFP1 (0.61) KCNK3KCNK9RXFP1F2RBRAF
SCHEMBL29211148 0.83 AVPR2 (0.64) KCNK3KCNK9RXFP1F2RPNLIP
SCHEMBL173604 0.82 KCNK3 (0.56) KCNK3KCNK9RXFP1F2RBRAF
SCHEMBL2105895 0.82 KCNK3 (0.70) KCNK3KCNK9RXFP1F2RPNLIP
SCHEMBL24474002 0.82 NPC1 (0.64) KCNK3KCNK9PNLIPKMT2AUSP2
SCHEMBL30587160 0.82 NPC1 (0.64) KCNK3KCNK9PNLIPKMT2AUSP2
SCHEMBL201210 0.81 KCNK3 (0.57) KCNK3KCNK9RXFP1F2RPNLIP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4376673-B1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B V (NL) 2025-01-01 EP disclosed
CN-118042960-A Filaments for oral care implements 联合利华知识产权控股有限公司 2024-05-14 CN disclosed
WO-2023006359-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B.V. (NL) 2023-02-02 WO disclosed