SCHEMBL30213409

SCHEMBL30213409

O=C1CCC(N2Cc3cc(NC(=O)c4ccccc4OC4CNC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 17/20 0.68
CSNK1A1 P48729 12/20 0.68
IKZF2 Q9UKS7 13/20 0.57
GSPT1 P15170 1/20 0.51
DDB1 Q16531 1/20 0.51
IKZF3 Q9UKT9 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30213319 0.93 CRBN (0.69) CRBNCSNK1A1IKZF2
SCHEMBL30213514 0.90 CRBN (0.66) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL30213232 0.88 CRBN (0.73) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL30213320 0.88 CRBN (0.65) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL24078810 0.85 CRBN (0.73) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL30213286 0.85 CRBN (0.73) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL30707716 0.84 CRBN (0.76) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL27471282 0.84 CRBN (0.76) CRBNCSNK1A1IKZF2GSPT1DDB1
SCHEMBL30707630 0.84 CRBN (0.76) CRBNCSNK1A1IKZF2
SCHEMBL30707582 0.83 CRBN (0.75) CRBNCSNK1A1IKZF2GSPT1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768768-A Galectin-3 inhibitors 百时美施贵宝公司 2023-03-07 CN disclosed