Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929590 | 1.00 | MEN1 (0.47) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL23929472 | 0.94 | MEN1 (0.48) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL30213167 | 0.94 | MEN1 (0.48) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL23929751 | 0.90 | MEN1 (0.49) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL23929767 | 0.90 | MEN1 (0.49) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL23929851 | 0.90 | MEN1 (0.49) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL23929754 | 0.90 | MEN1 (0.49) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL23929688 | 0.90 | MEN1 (0.49) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL23929715 | 0.90 | MEN1 (0.49) | MEN1KMT2ANPC1CCNA2CDK2 | |
| SCHEMBL23929827 | 0.90 | MEN1 (0.47) | MEN1KMT2ANPC1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697980-B | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-4139286-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2023-03-01 | — | — | EP | disclosed |
| CN-115697980-A | Substituted aminothiazoles as DGKZETA inhibitors for immune activation | 拜耳公司 | 2023-02-03 | — | — | CN | disclosed |