SCHEMBL30216268

CC(C)C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	F2	P00734	4/20	0.67

▸	CALCR	P30988	4/20	0.60

▸	HCRTR1	O43613	1/20	0.59

▸	HCRTR2	O43614	1/20	0.59

▸	MC4R	P32245	1/20	0.54

▸	CXCR4	P61073	2/20	0.54

▸	OPRM1	P35372	1/20	0.54

▸	OPRD1	P41143	1/20	0.54

▸	CRHR1	P34998	1/20	0.54

▸	CRHR2	Q13324	1/20	0.54

▸	NMUR2	Q9GZQ4	3/20	0.53

▸	NMUR1	Q9HB89	3/20	0.53

▸	APLNR	P35414	1/20	0.53

▸	CCKBR	P32239	1/20	0.53

▸	GLP1R	P43220	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30495631	0.88	F2 (0.66)	F2CALCRHCRTR1HCRTR2MC4R
SCHEMBL31031589	0.88	F2 (0.61)	F2CALCRHCRTR1HCRTR2MC4R
SCHEMBL30607329	0.88	F2 (0.68)	F2CALCRHCRTR1HCRTR2NMUR2
SCHEMBL31453812	0.87	F2 (0.67)	F2CALCRHCRTR1HCRTR2CRHR1
SCHEMBL31453815	0.87	F2 (0.67)	F2CALCRHCRTR1HCRTR2CRHR1
SCHEMBL30432714	0.87	CALCR (0.67)	F2CALCRHCRTR1HCRTR2CRHR1
SCHEMBL30576931	0.87	F2 (0.73)	F2CALCRHCRTR1HCRTR2CRHR1
SCHEMBL31073576	0.86	CALCR (0.62)	F2CALCRHCRTR1HCRTR2CXCR4
SCHEMBL32665685	0.86	F2 (0.52)	F2CALCRHCRTR1HCRTR2OPRM1
SCHEMBL31653878	0.86	CALCR (0.75)	F2CALCRHCRTR1HCRTR2CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3808371-B1	NOVEL ARTIFICIAL TEARS CONTAINING RECOMBINANT HUMAN LYSOZYME AND RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR	SHAANXI HUIKANG BIO TECH CO LTD (CN)	2023-11-22	—	—	EP	disclosed
CN-110604811-B	Artificial tear containing recombinant human lysozyme and recombinant human epidermal growth factor	陕西慧康生物科技有限责任公司	2023-01-31	—	—	CN	disclosed