Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 20/20 | 0.72 |
| ▸ | MET | P08581 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21431798 | 1.00 | AXL (0.72) | AXLMET | |
| SCHEMBL30216653 | 0.93 | AXL (0.79) | AXL | |
| SCHEMBL21431961 | 0.93 | AXL (0.79) | AXL | |
| SCHEMBL21431801 | 0.92 | AXL (0.77) | AXL | |
| SCHEMBL30216655 | 0.92 | AXL (0.77) | AXL | |
| SCHEMBL21431794 | 0.88 | AXL (0.86) | AXLMET | |
| SCHEMBL28518999 | 0.85 | AXL (0.87) | AXL | |
| SCHEMBL21408241 | 0.85 | AXL (0.82) | AXL | |
| SCHEMBL30216645 | 0.85 | AXL (0.82) | AXL | |
| SCHEMBL21408233 | 0.84 | AXL (1.00) | AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313213-B | 3-amino pyrazole compound and application thereof | 上海海和药物研究开发股份有限公司 | 2023-01-31 | — | — | CN | disclosed |