Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.34 |
| ▸ | VEGFA | P15692 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237452 | 1.00 | DRD1 (0.37) | DRD1PRKCQEPAS1VEGFAAR | |
| SCHEMBL31108531 | 0.88 | AR (0.37) | DRD1PRKCQEPAS1VEGFAAR | |
| SCHEMBL31108482 | 0.88 | DRD1 (0.36) | DRD1PRKCQEPAS1VEGFAAR | |
| SCHEMBL30967870 | 0.87 | AR (0.36) | DRD1PRKCQEPAS1VEGFAAR | |
| SCHEMBL27275534 | 0.85 | DRD1 (0.41) | DRD1PRKCQEPAS1ARRHEB | |
| SCHEMBL30938241 | 0.85 | DRD1 (0.41) | DRD1PRKCQEPAS1ARRHEB | |
| SCHEMBL27382323 | 0.84 | DRD1 (0.40) | DRD1PRKCQEPAS1VEGFAAR | |
| SCHEMBL31108584 | 0.83 | EPAS1 (0.33) | DRD1EPAS1VEGFAARTRPA1 | |
| SCHEMBL29337812 | 0.83 | BRD4 (0.38) | DRD1EPAS1VEGFAARRHEB | |
| SCHEMBL30938238 | 0.83 | BRD4 (0.38) | DRD1EPAS1VEGFAARRHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673141-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182751-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |