Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217052 | 0.94 | FFAR1 (0.38) | FFAR1CYP4F2CYP4A11 | |
| SCHEMBL29237659 | 0.94 | FFAR1 (0.38) | FFAR1CYP4F2CYP4A11 | |
| SCHEMBL30217088 | 0.89 | FFAR1 (0.34) | FFAR1CNR1CNR2CDK8TLR7 | |
| SCHEMBL29237454 | 0.89 | FFAR1 (0.34) | FFAR1CNR1CNR2CDK8TLR7 | |
| SCHEMBL30967940 | 0.89 | FFAR1 (0.33) | FFAR1CNR1CNR2CDK8TLR7 | |
| SCHEMBL30217296 | 0.89 | FFAR1 (0.33) | FFAR1CNR1CNR2CDK8TLR7 | |
| SCHEMBL29237209 | 0.89 | FFAR1 (0.33) | FFAR1CNR1CNR2CDK8TLR7 | |
| SCHEMBL29237441 | 0.89 | FFAR1 (0.33) | FFAR1CNR1CNR2CDK8TLR7 | |
| SCHEMBL30217056 | 0.89 | FFAR1 (0.33) | FFAR1CNR1CNR2CDK8TLR7 | |
| SCHEMBL30967901 | 0.88 | FFAR1 (0.32) | FFAR1CNR1CNR2CDK8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |