SCHEMBL30217416

SCHEMBL30217416

COC(=O)CCc1cccc(C(=O)c2cnc(-c3cc(Oc4c(F)cc5[nH]ccc5c4S(C)(=O)=O)ccc3F)[nH]2)c1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30967895 0.91 FFAR1 (0.33) FFAR1
SCHEMBL30217039 0.91 FFAR1 (0.33) FFAR1
SCHEMBL29237854 0.91 FFAR1 (0.33) FFAR1
SCHEMBL30217298 0.88 FFAR1 (0.32) FFAR1
SCHEMBL30967953 0.88 FFAR1 (0.32) FFAR1
SCHEMBL30217234 0.88 FFAR1 (0.32) FFAR1
SCHEMBL29237609 0.88 FFAR1 (0.32) FFAR1
SCHEMBL30967901 0.88 FFAR1 (0.32) FFAR1
SCHEMBL29237400 0.85 FFAR1 (0.31) FFAR1
SCHEMBL30217282 0.85 FFAR1 (0.31) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396179-A1 INDOLE COMPOUNDS AND METHODS OF USE GENZYME CORPORATION (US) 2024-07-10 — — EP disclosed
WO-2023034992-A1 INDOLE COMPOUNDS AND METHODS OF USE GENZYME CORPORATION (US) 2023-03-09 — — WO disclosed
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