Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25096304 | 1.00 | BACE1 (0.41) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL30217703 | 0.92 | BACE1 (0.40) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL25095784 | 0.92 | BACE1 (0.40) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL30217682 | 0.90 | BACE1 (0.43) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL25096852 | 0.90 | BACE1 (0.43) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL30312591 | 0.90 | BACE1 (0.40) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL25096320 | 0.90 | PTPN11 (0.46) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL30217787 | 0.90 | PTPN11 (0.46) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL25096700 | 0.89 | PTPN11 (0.39) | BACE1PTPN11MAPTMEN1TSHR | |
| SCHEMBL30217650 | 0.89 | PTPN11 (0.39) | BACE1PTPN11MAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395891-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |