Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | BHMT | Q93088 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.30 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Hydroxybutyric Acid, (+/-)- SCHEMBL30300556 | 0.83 | SLC22A16 (0.35) | CPT2CPT1ACA4SLC22A16MAPT | |
| SCHEMBL30160923 | 0.82 | CA4 (0.46) | CPT2CPT1ACA4SLC22A16 | |
| SCHEMBL29497518 | 0.82 | CA4 (0.46) | CPT2CPT1ACA4SLC22A16 | |
| Cadaverine Tartrate SCHEMBL29949245 | 0.81 | CA4 (0.37) | CA4SLC22A16 | |
| Hydrochloric Acid SCHEMBL30446529 | 0.80 | CA4 (0.45) | CPT2CPT1ACA4SLC22A16 | |
| Hydrochloric Acid SCHEMBL31574660 | 0.80 | CA4 (0.45) | CPT2CPT1ACA4SLC22A16 | |
| Pyruvate SCHEMBL29497569 | 0.79 | CA4 (0.41) | CA4 | |
| Fumaric Acid SCHEMBL30455914 | 0.76 | CA4 (0.38) | CA4 | |
| SCHEMBL29623681 | 0.75 | CPT2 (0.35) | CPT2CPT1ACA4SLC22A16MAPT | |
| SCHEMBL30065458 | 0.75 | CA4 (0.37) | CPT2CPT1ACA4SLC22A16 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125858-A1 | NUTRITIONAL COMPOSITION COMPRISING CARNITINE AND METHOD FOR TREATING OR PREVENTING AN INFECTION IN A MAMMAL | Lonza Consumer Health Inc. (US) | 2023-02-08 | — | — | EP | claimed |
| EP-4125858-A1 | NUTRITIONAL COMPOSITION COMPRISING CARNITINE AND METHOD FOR TREATING OR PREVENTING AN INFECTION IN A MAMMAL | Lonza Consumer Health Inc. (US) | 2023-02-08 | — | — | EP | disclosed |