Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 9/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.58 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.58 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21357098 | 1.00 | CSF1R (0.58) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL21357226 | 0.91 | CSF1R (0.54) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL30219290 | 0.91 | CSF1R (0.54) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL21357125 | 0.84 | NPC1 (0.51) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL30219266 | 0.84 | NPC1 (0.51) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL21357189 | 0.82 | CSF1R (0.64) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL25440054 | 0.81 | CSF1R (0.49) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL30574157 | 0.81 | CSF1R (0.49) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL21357142 | 0.81 | CSF1R (0.49) | CSF1RNTRK1NTRK2NTRK3NPC1 | |
| SCHEMBL30219253 | 0.81 | CSF1R (0.49) | CSF1RNTRK1NTRK2NTRK3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601790-B | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-116715625-A | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-111601790-B | Heteroaryl compounds as protein kinase inhibitors | 福建海西新药创制股份有限公司 | 2023-03-31 | — | — | CN | disclosed |