Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28986298 | 1.00 | MAP3K14 (0.77) | MAP3K14 | |
| SCHEMBL30219564 | 0.88 | MAP3K14 (0.70) | MAP3K14 | |
| SCHEMBL28986242 | 0.88 | MAP3K14 (0.70) | MAP3K14 | |
| SCHEMBL30219611 | 0.87 | MAP3K14 (1.00) | MAP3K14 | |
| SCHEMBL26268456 | 0.87 | MAP3K14 (1.00) | MAP3K14 | |
| SCHEMBL26269535 | 0.87 | MAP3K14 (1.00) | MAP3K14 | |
| SCHEMBL28986211 | 0.80 | MAP3K14 (0.66) | MAP3K14 | |
| SCHEMBL30219560 | 0.77 | MAP3K14 (0.80) | MAP3K14 | |
| SCHEMBL28986288 | 0.77 | MAP3K14 (0.80) | MAP3K14 | |
| SCHEMBL28986294 | 0.76 | MAP3K14 (1.00) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810110-B | Compound with 2-aminopyrimidine structure, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-01-24 | — | — | CN | disclosed |