Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | POLQ | O75417 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24896453 | 1.00 | HRH4 (0.48) | HRH4POLQTP53MAPTPYGL | |
| SCHEMBL30220516 | 0.83 | TP53 (0.50) | HRH4TP53MAPTPYGLLMNA | |
| SCHEMBL24896460 | 0.83 | TP53 (0.50) | HRH4TP53MAPTPYGLLMNA | |
| SCHEMBL24896452 | 0.82 | HRH4 (0.53) | HRH4POLQSMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL24896445 | 0.75 | HRH4 (0.47) | HRH4POLQTP53KMT2A | |
| SCHEMBL30220537 | 0.75 | HRH4 (0.47) | HRH4POLQTP53KMT2A | |
| SCHEMBL30220515 | 0.74 | AR (0.51) | MAPTPYGLSYKKMT2A | |
| SCHEMBL24896231 | 0.74 | AR (0.51) | MAPTPYGLSYKKMT2A | |
| SCHEMBL1145047 | 0.72 | HRH4 (0.60) | HRH4MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL24896470 | 0.72 | SYK (0.47) | TP53PYGLSYKKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370207-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023287704-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2023-01-19 | — | — | WO | disclosed |