Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24896365 | 1.00 | HSD17B10 (0.42) | HSD17B10KDM4EALDH1A1HPGDMCL1 | |
| SCHEMBL30220568 | 0.82 | KDM4E (0.45) | HSD17B10KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24896374 | 0.79 | MCL1 (0.46) | HSD17B10KDM4EALDH1A1HPGDMCL1 | |
| SCHEMBL20504453 | 0.78 | MCL1 (0.45) | HSD17B10KDM4EALDH1A1HPGDMCL1 | |
| SCHEMBL24896300 | 0.77 | GRM4 (0.38) | — | |
| SCHEMBL25003332 | 0.77 | HASPIN (0.31) | HSD17B10KDM4EHTTSMN1; SMN2 | |
| SCHEMBL24896258 | 0.75 | KDM4E (0.50) | HSD17B10KDM4EALDH1A1HPGDMCL1 | |
| SCHEMBL24896576 | 0.75 | MCL1 (0.43) | HSD17B10KDM4EALDH1A1HPGDMCL1 | |
| SCHEMBL24896316 | 0.75 | MCL1 (0.43) | HSD17B10KDM4EALDH1A1HPGDMCL1 | |
| SCHEMBL24896308 | 0.73 | MCL1 (0.41) | HSD17B10KDM4EALDH1A1HPGDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370207-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023287704-A1 | BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2023-01-19 | — | — | WO | disclosed |