Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.61 |
| ▸ | CDK7 | P50613 | 2/20 | 0.58 |
| ▸ | CCNH | P51946 | 2/20 | 0.58 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24900843 | 1.00 | EGFR (0.61) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL24900837 | 0.92 | EGFR (0.59) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL30221505 | 0.92 | EGFR (0.59) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL30221580 | 0.90 | EGFR (0.62) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL24900816 | 0.90 | EGFR (0.62) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL24900634 | 0.88 | EGFR (0.60) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL30221363 | 0.88 | EGFR (0.60) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL24900840 | 0.87 | EGFR (0.65) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL30221613 | 0.87 | EGFR (0.65) | EGFRCDK7CCNHIGF1RKCNH2 | |
| SCHEMBL24900615 | 0.86 | EGFR (0.58) | EGFRCDK7CCNHIGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |