Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993933 | 1.00 | PPARD (0.34) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL23994040 | 0.90 | MTOR (0.32) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL23994037 | 0.90 | MTOR (0.32) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL23991557 | 0.85 | MTOR (0.38) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL30224465 | 0.85 | MTOR (0.38) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL30181590 | 0.85 | MTOR (0.35) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL23993405 | 0.85 | MTOR (0.35) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL29467452 | 0.85 | MTOR (0.37) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL23994049 | 0.84 | CYP1A2 (0.37) | PPARDMTORSYKPIK3CDABL1 | |
| SCHEMBL23994054 | 0.84 | CYP1A2 (0.37) | PPARDMTORSYKPIK3CDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143194-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |