Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25005896 | 0.92 | NPSR1 (0.41) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30224893 | 0.92 | NPSR1 (0.41) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30224274 | 0.92 | NPSR1 (0.41) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23994494 | 0.90 | NPSR1 (0.40) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30224427 | 0.90 | NPSR1 (0.40) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23994719 | 0.89 | NPSR1 (0.39) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28947367 | 0.89 | NPSR1 (0.40) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30224334 | 0.89 | NPSR1 (0.40) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23994264 | 0.88 | NPSR1 (0.39) | NPSR1ATMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30181620 | 0.88 | NPSR1 (0.39) | NPSR1ATMMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143194-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |