Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30224579 | 0.92 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL30181463 | 0.83 | NT5E (0.33) | — | |
| SCHEMBL25005003 | 0.83 | GRIN1 (0.31) | — | |
| SCHEMBL23993425 | 0.83 | GRIN1 (0.31) | — | |
| SCHEMBL30181579 | 0.83 | GRIN1 (0.31) | — | |
| SCHEMBL23994136 | 0.83 | NT5E (0.33) | — | |
| SCHEMBL30181922 | 0.83 | NT5E (0.33) | — | |
| SCHEMBL23991654 | 0.82 | PDE2A (0.30) | — | |
| SCHEMBL25005868 | 0.82 | PDE2A (0.30) | — | |
| SCHEMBL23993392 | 0.82 | CYP17A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4422756-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023077030-A1 | CD73 COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| EP-4143194-A1 | CD73 INHIBITING 2,4-DIOXOPYRIMIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-03-08 | — | — | EP | disclosed |